Sucralose is produced through a complex multistep synthesis process that involves the selective chlorination of sucrose. This process effectively substitutes three hydroxyl groups in the sucrose molecule with chlorine atoms, transforming it into a potent artificial sweetener.

Also Known As

Sucralose is known by various names and designations, reflecting its chemical structure and commercial applications, including:

  • 1′,4,6′-Trichlorogalactosucrose
  • Trichlorosucrose
  • E955
  • 4,1′,6′-Trichloro-4,1′,6′-trideoxygalactosucrose (TGS)
  • Splenda


Sucralose is widely used as an artificial sweetener and sugar substitute in a broad range of food and beverage products. Due to its intense sweetness, it is a popular choice for reducing calorie intake without sacrificing taste. It is found in products such as soft drinks, baking goods, gums, and dietary supplements.


As an artificial sweetener, sucralose stands out for its extraordinary sweetness, which ranges from 320 to 1,000 times sweeter than sucrose. This makes it considerably sweeter than other artificial sweeteners, including aspartame, acesulfame potassium, and sodium saccharin. Its popularity is due in part to its sweetness, as well as its stability under heat and across a broad range of pH conditions, making it versatile for both cooking and manufacturing processes. Key characteristics include:

  • Exceptionally sweet, with a potency up to 1,000 times that of sucrose
  • Stable under heat and across a variety of pH levels
  • Widely used in a variety of low-calorie and diet food products

Common Dosage

The acceptable daily intake for sucralose has been set at 5 milligrams per kilogram of body weight per day. This guideline helps ensure that consumption remains within safe limits, allowing individuals to enjoy the sweetening benefits of sucralose without adverse effects.


Sucralose offers a high-intensity sweetness that far exceeds that of natural sugar, making it a favored choice for those looking to reduce sugar and calorie intake. Its stability and versatility across various applications further enhance its appeal. Key takeaways include:

  • Offers a significantly sweeter alternative to sugar with fewer calories
  • Suitable for a wide range of dietary and manufacturing applications
  • Safe daily consumption level established at 5 mg/kg of body weight

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