Sodium Hyaluronate


Sodium Hyaluronate was traditionally derived from rooster combs but is now predominantly obtained from plant sources like soybean and corn. This extraction process involves a bacterial fermentation technique, marking a shift towards more sustainable and ethical production methods.

Also Known As

This compound is known by various names, emphasizing its versatility and widespread application:

  • Sodium Hyaluronate Solution
  • Sodium Salt Hyaluronic Acid
  • Healon
  • Hyalurone Sodium
  • Si-4402
  • Sl-1010
  • SPH

These names reflect its chemical nature and its various formulations in healthcare and cosmetic products.


Sodium Hyaluronate is used in a broad spectrum of applications, thanks to its unique properties. Its uses extend across medical and cosmetic fields:

  • As the main ingredient in Restylane, treating facial volume loss and wrinkles through injections.
  • In medical treatments for knee pain associated with arthritis.
  • For its moisturizing benefits in topical skin care products, known for its gentle and non-irritating properties.


Sodium Hyaluronate, the sodium salt of hyaluronic acid, plays a crucial role in the body, found naturally in joint fluids, the eye’s vitreous humor, and the skin. It’s celebrated for its medical and cosmetic applications, from injectable fillers like Restylane to treatments for arthritis and skincare products.

Key points include:

  • Naturally present in the body, supporting joint and skin health.
  • Used in cosmetic procedures to restore facial volume and smooth wrinkles.
  • Provides significant moisturizing benefits, making it a favorite in skin care formulations.

Common Dosage

The dosage of Sodium Hyaluronate can vary widely depending on its use, ranging from 10 mg to 20 mg. This dosage flexibility allows it to be effectively tailored to specific medical or cosmetic needs.


Sodium Hyaluronate stands out for its diverse applications, from enhancing beauty through dermal fillers to providing relief in arthritis treatments and hydrating the skin. Its transition from animal to plant-based sources reflects advancements in production methods, aligning with modern ethical standards.

Key summary points include:

  • Integral to both medical treatments and cosmetic procedures.
  • Offers moisturizing and healing properties, beneficial for skin and joint health.
  • Recommended dosages vary, emphasizing the need for professional guidance in its application.

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