Origin

Orotic acid monohydrate is naturally produced in the human body through two primary pathways: by a mitochondrial enzyme known as dihydroorotate dehydrogenase and by a cytoplasmic enzyme involved in the pyrimidine synthesis pathway. These processes are essential for the body’s production of pyrimidine nucleotides, which are vital components of DNA and RNA.

Also Known As

Orotic acid monohydrate is known by several other names, including:

• Vitamin B13 (obsolete)
• Pyrimidinecarboxylic acid
• 4-Ureidocarboxylic acid

Usages

This compound is commonly utilized in the field of dietary supplements, serving as a mineral carrier. It is particularly noted for enhancing the bioavailability of minerals, most notably in the formulation of lithium orotate supplements. The use of orotic acid monohydrate improves how effectively the body can absorb and utilize these minerals.

Overview

Orotic acid monohydrate is a chemical compound belonging to the pyrimidinedione and carboxylic acid families. Its main application in health and nutrition is as a component of dietary supplements, where it acts as a carrier to increase mineral bioavailability. This is particularly significant for supplements containing lithium, as the combination with orotic acid facilitates easier absorption and utilization by the body. Key points include:

• Acts as a mineral carrier in dietary supplements.
• Improves the bioavailability of minerals, notably lithium.
• Produced naturally in the human body through specific enzymatic pathways.

Common Dosage

There is no universally agreed-upon dosage for orotic acid monohydrate as its use and efficacy can vary depending on the specific health supplement and individual needs. It is typically formulated in combination with minerals like lithium in dietary supplements.

Summary

Orotic acid monohydrate plays a crucial role in nutrition and health as a mineral carrier, enhancing the bioavailability of supplements, particularly those containing lithium. It is naturally synthesized in the body and utilized in dietary supplements to support better mineral absorption and utilization. Key takeaways include:

• Naturally produced in the body and essential for nucleotide synthesis.
• Used to improve mineral bioavailability in supplements.
• Commonly associated with lithium orotate formulations.

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