Methylcobalamin (Vitamin B12)


Methylcobalamin is synthesized in a laboratory setting. This process involves the reduction of cyanocobalamin, a synthetic form of vitamin B12, using sodium borohydride in an alkaline environment. The procedure is completed by incorporating methyl iodide into the mix.

Also Known As

Methylcobalamin is known by various names, reflecting its widespread recognition and utilization in the medical and nutritional fields:

  • Mecobalamin
  • MeCbl
  • Meb12


Methylcobalamin serves as a crucial component in medical treatments and nutritional supplements. Its primary use is to combat vitamin B12 deficiencies, which can lead to significant health issues if unaddressed. Moreover, it finds application in treating various forms of neuropathy, including peripheral and diabetic neuropathy, and is explored as an initial treatment option for amyotrophic lateral sclerosis.


As a variant of vitamin B12, Methylcobalamin plays a vital role in maintaining nerve health and contributing to the formation of red blood cells. It is physiologically equivalent to vitamin B12, making it an effective tool against vitamin B12 deficiency and its associated conditions. The significance of Methylcobalamin extends to:

  • Prevention and treatment of vitamin B12 deficiencies
  • Therapeutic use in peripheral and diabetic neuropathy
  • Investigation as a potential treatment for amyotrophic lateral sclerosis

Common Dosage

The recommended dosage of Methylcobalamin varies, ranging from 1 to 25 micrograms (mcg) per day, depending on the individual’s health status and the specific condition being treated.


Methylcobalamin is a laboratory-produced form of vitamin B12, essential for addressing deficiencies and treating various neuropathic conditions. Its key highlights include:

  • Synthetic creation through the reduction of cyanocobalamin
  • Effective in treating vitamin B12 deficiencies and neuropathy
  • Dosages ranging from 1 to 25 mcg per day For more information, call Nutrasky today.

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