L-Histidine is sourced from both the body’s own production and a variety of foods and supplements. It is abundant in protein-rich foods such as red meats (beef and lamb), poultry (chicken and turkey), fish, soy products (tofu), beans, dairy (milk), seeds, nuts, whole grains, and eggs. This amino acid plays a vital role in numerous bodily functions, making its presence essential in a balanced diet.

Also Known As

L-Histidine is recognized by several scientific names, emphasizing its chemical structure and biological significance. These include:

  • (S)-4-(2-Amino-2-carboxyethyl)imidazole
  • (S)-α-Amino-1H-imidazole-4-propanoic acid
  • (S)-alpha-amino-1H-Imidazole-4-propanoic acid
  • (S)-alpha-Amino-1H-imidazole-4-propionic acid
  • (S)-α-amino-1H-Imidazole-4-propanoic acid


L-Histidine is utilized extensively across various fields due to its significant role in human health and nutrition. It is crucial in the medical field for its therapeutic benefits, in nutritional supplements to support overall health, and in the food industry to enhance the nutritional value of products. Its importance in maintaining nerve health, immune system function, and recovery processes makes it a valued ingredient in health and wellness products.


L-Histidine is a conditionally essential amino acid and one of the 23 proteinogenic amino acids that are integral to protein synthesis in the human body. It has several critical functions:

  • Essential for the formation of myelin sheaths, protecting nerve cells from damage.
  • Protects the body against radiation damage and assists in lowering blood pressure.
  • Supports the recovery process after injuries and boosts the immune system.

L-Histidine is also vital for the production of histamines, which play a key role in immune response and gastric acid secretion.

Common Dosage

The common dosage of L-Histidine is recommended to be 10 mg per kg of body weight per day. This dosage can support its various roles in the body, particularly for individuals with increased nutritional needs or those recovering from injuries.


L-Histidine is an amino acid with a wide array of benefits, from supporting nerve protection to aiding the immune system. It is found in a diverse range of foods and is also produced by the body, highlighting its importance in both diet and physiological processes. Key points include:

  • Supports nerve protection and the immune system.
  • Found in a wide variety of foods and produced by the body.
  • Recommended dosage is 10 mg/kg of body weight per day.

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