L-Citrulline Base


L-Citrulline is a unique amino acid that finds its origins not only within the human body but also in various supplements and foods, most notably in watermelon. This amino acid plays a crucial role in several bodily functions, particularly in the synthesis of proteins and the regulation of blood flow.

Also Known As

L-Citrulline is known by its scientific name but also goes by various aliases, depending on its application and context:

  • Citrulline
  • L-Citrulline Malate (when bound with malic acid)
  • Watermelon Extract (when derived from watermelon)


The applications of L-Citrulline are diverse, ranging from dietary supplements to enhance athletic performance to medical uses for improving cardiovascular health. It’s widely used by athletes and bodybuilders to boost energy levels, enhance muscle recovery, and improve endurance. Additionally, its potential to improve blood flow makes it a candidate for cardiovascular health supplements, particularly for those looking to manage blood pressure and improve arterial health.


L-Citrulline stands out in the nutritional and medical fields due to its ability to enhance the production of nitric oxide, which plays a pivotal role in vasodilation and blood flow. This amino acid is metabolized into L-arginine and nitric oxide, thereby contributing to several health benefits, including improved muscle oxygenation during exercise, reduced fatigue, and better cardiovascular health. Here are key points about L-Citrulline:

  • Boosts nitric oxide production, improving blood flow and reducing blood pressure.
  • Enhances athletic performance by aiding in the reduction of muscle fatigue.
  • Contributes to better cardiovascular health by supporting arterial flexibility and circulation.

Common Dosage

The common dosage for L-Citrulline varies based on the intended use, but dosages up to 9 grams daily are considered safe and effective for most adults. This dosage can help achieve the desired effects in athletic performance enhancement and cardiovascular health improvement.


L-Citrulline is a versatile and beneficial amino acid known for its ability to improve blood flow, enhance athletic performance, and support cardiovascular health. It is naturally occurring in the body and can be supplemented through diet or nutritional supplements. Key takeaways include:

  • Natural production in the body, with additional sources including supplements and watermelon.
  • Known to enhance nitric oxide production, promoting vasodilation and improved blood flow.
  • Commonly used to improve athletic performance and support cardiovascular health.

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