L-Arginine L-Pyroglutamate


L-Arginine Pyroglutamate is sourced from dietary supplements and various food sources, including vegetables, fruit, dairy products, and meat, providing a wide availability for consumption and supplementation.

Also Known As

This compound is recognized by several scientific names, including:

  • Arginine pyroglutamate
  • (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid
  • (2S)-5-oxopyrrolidine-2-carboxylic acid (1:1)


L-Arginine Pyroglutamate is valued for its role in promoting increased levels of human growth hormone, which is crucial for the development of lean muscle tissue and the reduction of fat. This amino acid is particularly significant as growth hormone levels naturally decline with age, leading to increased fat accumulation and muscle loss. Supplementation with L-Arginine Pyroglutamate, especially in conjunction with weight training, has shown to significantly enhance muscle growth and reduce body fat.


L-Arginine Pyroglutamate, a semi-essential amino acid bonded to a pyroglutamate molecule, offers substantial benefits for enhancing physical fitness and combating age-related muscle loss. Its key benefits include:

  • Promoting increased levels of human growth hormone, aiding in muscle growth and fat loss.
  • Supporting protein synthesis for faster muscle development and preventing muscle breakdown during intensified exercise.
  • Demonstrating effectiveness in controlled trials, showing significant fat loss and muscle gain when used with a weight training program.

Common Dosage

The recommended dosage for L-Arginine Pyroglutamate ranges between 1000 to 1500 mg, catering to its effectiveness in supporting muscle growth and hormone balance.


L-Arginine Pyroglutamate stands out for its ability to enhance growth hormone levels, supporting lean muscle development and fat loss, particularly as individuals age. It demonstrates a crucial role in improving protein synthesis and exercise outcomes. Key points include:

  • Sourced from a variety of foods and supplements, ensuring accessibility for dietary intake.
  • Supports increased growth hormone levels, promoting muscle growth and fat reduction.
  • Recommended intake is between 1000 to 1500 mg for optimal benefits.

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