Diindolylmethane (DIM)


Diindolylmethane (DIM) is naturally derived from a variety of cruciferous vegetables, including but not limited to cabbage, Brussels sprouts, cauliflower, and broccoli. These vegetables are known for their nutritional value and health benefits, among which DIM plays a significant role.

Also Known As

Diindolylmethane, commonly referred to as DIM, is known by several chemical names, highlighting its structural complexity and significance in nutritional science. Here are its alternate names:

  • 3-(1H-Indol-3-ylmethyl)-1H-indole
  • 3,3′-Methylenebis-1H-indole
  • DIM


DIM is prominently used for its potential in cancer prevention, particularly in cases of breast, uterine, and colorectal cancer. Beyond its cancer-preventative properties, DIM is researched for its unique interaction with estrogen in the body, where it may mimic or block estrogen effects under varying conditions. This dual capability makes it a compound of interest in hormonal balance and health.


Diindolylmethane (DIM) emerges as a noteworthy compound formed in the human body from plant substances found in cruciferous vegetables. These vegetables are celebrated for their potential to shield the body against various forms of cancer, thanks to DIM and related chemicals such as indole-4-carbinol. Key points to note include:

  • DIM is derived from a diet rich in cruciferous vegetables.
  • It is studied for its cancer-preventative properties and hormone-related actions.
  • DIM may either mimic or block the effects of estrogen, depending on bodily conditions.

Common Dosage

A common dosage observed in studies is 100 mg of DIM, which has been noted to alter urinary estrogens in a manner thought to reflect a reduction in estrogenicity. This dosage highlights DIM’s potential impact on hormonal balance and its relevance in dietary supplements.


Diindolylmethane (DIM) is a compound of interest derived from cruciferous vegetables known for its potential in cancer prevention and hormonal balance. Through its dual action of mimicking or blocking estrogen, DIM offers a complex but promising avenue for health benefits. Key highlights include:

  • Natural derivation from cruciferous vegetables.
  • Potential in cancer prevention and hormonal balance.
  • Common dosage of 100 mg reflects its impact on estrogenicity.

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